Waveguide-Based Biosensors for Low-Level Concentration Fumonisin B1 Detection

Abstract

Optical phenomena such as polarization, phosphorescence, fluorescence and interference have achieved great success in the field of bio sensing applications. Optical waveguides biosensor system are constituted of material possess high refractive index and high permittivity surrounded by lower refractive indices materials as cladding or media to be sensed. This arrangement give rise to light propagates across the core of the waveguide via total internal reflection, during this propagation, evanescent field arises around core in the cladding area and decreases exponentially as away from the cladding-core interface. This phenomenon has been exploited in this work to detect the biological molecules. Presence of the targeted biological molecules in the evanescent field area effect on the parameters of the reflected light beam particularly the polarization state. This mechanism of sensing has been applied in this work to detect to detect mycotoxins molecules. The results showed the success of this approach and its ability to sense very low concentrations in range of 0.01ng/mL, which meets and exceeds the required detection limits for environmental safety.