AP0981 Impact of Al2O3-PSA on Biological and Mechanical Properties of Soft Acrylic used in Medical Applications

Abstract

Among orthopedic surgery materials, poly (methylmethacrylate) (PMMA) is most commonly used for its excellent mechanical properties and rapid self-setting time. However, PMMA has been a major hurdle, namely, their poor antimicrobial (i.e., adhesion) properties, can accelerate infections and cause bacterial colonization and to have poor bioactivity, which must be improved by prepared anovel organic-inorganic PMMA composite. The powders of Aluminum oxide (Al₂O₃), peach kernal seed (PKS) with particles size in a range of (73 nm) and (9.5 nm), respectivly, were added to PMMA cement. Their influence on FTIR, compression strength, hardness, wettability, antibacterial and cytotoxicity properties of PMMA was assessed. The result showed a considerably improvement in the values of these properties for both groups of bio composite specimens comparing with neat PMMA. All bio composite specimens reinforced with peach kernal seeds PKS powder in nanometre size showed the highest properties as compared with the bio composite specimens strengthened by nano Aluminium oxide Al₂O₃. On the basis of these results, it can be conclusion that the addition of nano fillings nanoparticles to bio PMMA material, is one of the promising materials in biomedical application.